Understanding low sensitivity of community-based HIV rapid testing: experiences from the HPTN 071 (PopART) trial in Zambia and South Africa.
Identifieur interne : 000069 ( Main/Exploration ); précédent : 000068; suivant : 000070Understanding low sensitivity of community-based HIV rapid testing: experiences from the HPTN 071 (PopART) trial in Zambia and South Africa.
Auteurs : Peter Bock [Afrique du Sud] ; Comfort Phiri [Zambie] ; Estelle Piwowar-Manning [États-Unis] ; Barry Kosloff [Zambie] ; Nomtha Mandla [Afrique du Sud] ; Alicia Young [États-Unis] ; Anelet James [Afrique du Sud] ; Ab Schaap [Zambie] ; Michelle Scheepers [Afrique du Sud] ; Deborah Donnell [États-Unis] ; Sam Griffith [États-Unis] ; Wafaa El-Sadr [États-Unis] ; Kwame Shanaube [Zambie] ; Nulda Beyers [Afrique du Sud] ; Richard Hayes [Royaume-Uni] ; Sarah Fidler [Royaume-Uni] ; Helen Ayles [Zambie]Source :
- Journal of the International AIDS Society [ 1758-2652 ] ; 2017.
Abstract
Population-wide HIV testing services (HTS) must be delivered in order to achieve universal antiretroviral treatment (ART) coverage. To accurately deliver HTS at such scale, non-facility-based HIV point-of-care testing (HIV-POCT) is necessary but requires rigorous quality assurance (QA). This study assessed the performance of community-wide HTS in Zambia and South Africa (SA) as part of the HPTN 071 (PopART) study and explores the impact of quality improvement interventions on HTS performance.
DOI: 10.7448/IAS.20.7.21780
PubMed: 28872272
Affiliations:
- Afrique du Sud, Royaume-Uni, Zambie, États-Unis
- Angleterre, Caroline du Nord, Grand Londres, Maryland, Washington (État), État de New York
- Londres
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Cape</wicri:regionArea><wicri:noRegion>Western Cape</wicri:noRegion></affiliation></author><author><name sortKey="Phiri, Comfort" sort="Phiri, Comfort" uniqKey="Phiri C" first="Comfort" last="Phiri">Comfort Phiri</name><affiliation wicri:level="1"><nlm:affiliation>Zambart, University of Zambia, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>Zambart, University of Zambia, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Piwowar Manning, Estelle" sort="Piwowar Manning, Estelle" uniqKey="Piwowar Manning E" first="Estelle" last="Piwowar-Manning">Estelle Piwowar-Manning</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, HPTN Laboratory Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, HPTN Laboratory Center, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Kosloff, Barry" sort="Kosloff, Barry" uniqKey="Kosloff B" first="Barry" last="Kosloff">Barry Kosloff</name><affiliation wicri:level="1"><nlm:affiliation>Zambart, University of Zambia, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>Zambart, University of Zambia, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Mandla, Nomtha" sort="Mandla, Nomtha" uniqKey="Mandla N" first="Nomtha" last="Mandla">Nomtha Mandla</name><affiliation wicri:level="1"><nlm:affiliation>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape</wicri:regionArea><wicri:noRegion>Western Cape</wicri:noRegion></affiliation></author><author><name sortKey="Young, Alicia" sort="Young, Alicia" uniqKey="Young A" first="Alicia" last="Young">Alicia Young</name><affiliation wicri:level="2"><nlm:affiliation>Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="James, Anelet" sort="James, Anelet" uniqKey="James A" first="Anelet" last="James">Anelet James</name><affiliation wicri:level="1"><nlm:affiliation>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape</wicri:regionArea><wicri:noRegion>Western Cape</wicri:noRegion></affiliation></author><author><name sortKey="Schaap, Ab" sort="Schaap, Ab" uniqKey="Schaap A" first="Ab" last="Schaap">Ab Schaap</name><affiliation wicri:level="1"><nlm:affiliation>Zambart, University of Zambia, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>Zambart, University of Zambia, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Scheepers, Michelle" sort="Scheepers, Michelle" uniqKey="Scheepers M" first="Michelle" last="Scheepers">Michelle Scheepers</name><affiliation wicri:level="1"><nlm:affiliation>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape</wicri:regionArea><wicri:noRegion>Western Cape</wicri:noRegion></affiliation></author><author><name sortKey="Donnell, Deborah" sort="Donnell, Deborah" uniqKey="Donnell D" first="Deborah" last="Donnell">Deborah Donnell</name><affiliation wicri:level="2"><nlm:affiliation>Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Griffith, Sam" sort="Griffith, Sam" uniqKey="Griffith S" first="Sam" last="Griffith">Sam Griffith</name><affiliation wicri:level="2"><nlm:affiliation>Science Facilitation Department, FHI 360, Durham, NC, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Science Facilitation Department, FHI 360, Durham, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="El Sadr, Wafaa" sort="El Sadr, Wafaa" uniqKey="El Sadr W" first="Wafaa" last="El-Sadr">Wafaa El-Sadr</name><affiliation wicri:level="2"><nlm:affiliation>ICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>ICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Shanaube, Kwame" sort="Shanaube, Kwame" uniqKey="Shanaube K" first="Kwame" last="Shanaube">Kwame Shanaube</name><affiliation wicri:level="1"><nlm:affiliation>Zambart, University of Zambia, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>Zambart, University of Zambia, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author><author><name sortKey="Beyers, Nulda" sort="Beyers, Nulda" uniqKey="Beyers N" first="Nulda" last="Beyers">Nulda Beyers</name><affiliation wicri:level="1"><nlm:affiliation>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Western Cape</wicri:regionArea><wicri:noRegion>Western Cape</wicri:noRegion></affiliation></author><author><name sortKey="Hayes, Richard" sort="Hayes, Richard" uniqKey="Hayes R" first="Richard" last="Hayes">Richard Hayes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fidler, Sarah" sort="Fidler, Sarah" uniqKey="Fidler S" first="Sarah" last="Fidler">Sarah Fidler</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medicine, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ayles, Helen" sort="Ayles, Helen" uniqKey="Ayles H" first="Helen" last="Ayles">Helen Ayles</name><affiliation wicri:level="1"><nlm:affiliation>Zambart, University of Zambia, Lusaka, Zambia.</nlm:affiliation><country xml:lang="fr">Zambie</country><wicri:regionArea>Zambart, University of Zambia, Lusaka</wicri:regionArea><wicri:noRegion>Lusaka</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the International AIDS Society</title><idno type="eISSN">1758-2652</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Population-wide HIV testing services (HTS) must be delivered in order to achieve universal antiretroviral treatment (ART) coverage. To accurately deliver HTS at such scale, non-facility-based HIV point-of-care testing (HIV-POCT) is necessary but requires rigorous quality assurance (QA). This study assessed the performance of community-wide HTS in Zambia and South Africa (SA) as part of the HPTN 071 (PopART) study and explores the impact of quality improvement interventions on HTS performance.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li><li>Royaume-Uni</li><li>Zambie</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Caroline du Nord</li><li>Grand Londres</li><li>Maryland</li><li>Washington (État)</li><li>État de New York</li></region><settlement><li>Londres</li></settlement></list><tree><country name="Afrique du Sud"><noRegion><name sortKey="Bock, Peter" sort="Bock, Peter" uniqKey="Bock P" first="Peter" last="Bock">Peter Bock</name></noRegion><name sortKey="Beyers, Nulda" sort="Beyers, Nulda" uniqKey="Beyers N" first="Nulda" last="Beyers">Nulda Beyers</name><name sortKey="James, Anelet" sort="James, Anelet" uniqKey="James A" first="Anelet" last="James">Anelet James</name><name sortKey="Mandla, Nomtha" sort="Mandla, Nomtha" uniqKey="Mandla N" first="Nomtha" last="Mandla">Nomtha Mandla</name><name sortKey="Scheepers, Michelle" sort="Scheepers, Michelle" uniqKey="Scheepers M" first="Michelle" last="Scheepers">Michelle Scheepers</name></country><country name="Zambie"><noRegion><name sortKey="Phiri, Comfort" sort="Phiri, Comfort" uniqKey="Phiri C" first="Comfort" last="Phiri">Comfort Phiri</name></noRegion><name sortKey="Ayles, Helen" sort="Ayles, Helen" uniqKey="Ayles H" first="Helen" last="Ayles">Helen Ayles</name><name sortKey="Kosloff, Barry" sort="Kosloff, Barry" uniqKey="Kosloff B" first="Barry" last="Kosloff">Barry Kosloff</name><name sortKey="Schaap, Ab" sort="Schaap, Ab" uniqKey="Schaap A" first="Ab" last="Schaap">Ab Schaap</name><name sortKey="Shanaube, Kwame" sort="Shanaube, Kwame" uniqKey="Shanaube K" first="Kwame" last="Shanaube">Kwame Shanaube</name></country><country name="États-Unis"><region name="Maryland"><name sortKey="Piwowar Manning, Estelle" sort="Piwowar Manning, Estelle" uniqKey="Piwowar Manning E" first="Estelle" last="Piwowar-Manning">Estelle Piwowar-Manning</name></region><name sortKey="Donnell, Deborah" sort="Donnell, Deborah" uniqKey="Donnell D" first="Deborah" last="Donnell">Deborah Donnell</name><name sortKey="El Sadr, Wafaa" sort="El Sadr, Wafaa" uniqKey="El Sadr W" first="Wafaa" last="El-Sadr">Wafaa El-Sadr</name><name sortKey="Griffith, Sam" sort="Griffith, Sam" uniqKey="Griffith S" first="Sam" last="Griffith">Sam Griffith</name><name sortKey="Young, Alicia" sort="Young, Alicia" uniqKey="Young A" first="Alicia" last="Young">Alicia Young</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Hayes, Richard" sort="Hayes, Richard" uniqKey="Hayes R" first="Richard" last="Hayes">Richard Hayes</name></region><name sortKey="Fidler, Sarah" sort="Fidler, Sarah" uniqKey="Fidler S" first="Sarah" last="Fidler">Sarah Fidler</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28872272" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SidaSubSaharaV1
| This area was generated with Dilib version V0.6.32. |  |